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References:


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SEX

Viagra:

1. Guay AT, Perez JB, Jacobson J, Newton RA: Efficacy and safety of sildenafil citrate for treatment of erectile dysfunction in a population with associated organic risk factors, J. Androl., 22(5):793-797, 2001.

2. Kloner RA: Erectile dysfunction and cardiovascular risk, Hosp. Pract., 36(8):41-44, 49-51, 2001.

3. Kloner RA: Sex and the patient with cardiovascular risk factors: Focus on sildenafil, Am. J. Med., 109(9A):13S-21S, 2000.

4. Kloner RA, Zusman RM: Cardiovascular effects of sildenafil citrate and recommendations for its use, Am. J. Cardiol., 84(5B):11N-17N, 1999.

5. Martinez-Jabaloyas JM, Gil-Salom M, Villamon-Fort R, Pastor-Hernandez F, Martinez-Garcia R, Garcia-Sisamon F: Prognostic factors for response to sildenafil in patients with erectile dysfunction, Eur. Urol., 40(6):641-647, 2001.

6. Shabsigh R: Recent developments in male sexual dysfunction, Curr. Psychiatry Rep., 2(3):196-200, 2000.

7. Vitezic D: A risk-benefit assessment of sildenafil in the treatment of erectile dysfunction, Drug Saf., 24(4):255-265, 2001.

DANGER

Migraines & Rebound Headache:

1. Bigal ME, Sheftell FD, Rapoport AM, Tepper SJ, Lipton RB: Chronic daily headache: identification of factors associated with induction and transformation, Headache, 42(7):575-581, 2002

2. Silberstein SD, Liu D: Drug overuse and rebound headache, Curr. Pain Headache Rep., 6(3):240-247, 2002.

3. Ward TN: Headache disorders in the elderly, Curr. Treat. Options Neurol., 4(5):403-408, 2002.

Headache & Stroke:

1. Landtblom AM, Fridriksson S, Boivie J,Hillman J, Johansson G, Johansson I: Sudden onset headache: a prospective study of features, incidence and causes, Cephalalgia, 22(5):354-360, 2002.

2. Rathore SS, Hinn AR, Cooper LS, Tyroler HA, Rosamond WD: Characterization of incident stroke signs and symptoms: findings from the atherosclerosis risk in communities study, Stroke, 33(11):2718-2721, 2002.

3. www.healthology.com/printer_friendly.asp?f=headache&c=headache_stoke.

NUTRITION

Fruits & Vegetables:

1. Agudo A, Esteve MG, Pallares C, Martinez-Ballarin I, Fabregat X, Malats N, Machengs I, Badia A, Gonzalez CA: Vegetable and fruit intake and the risk of lung cancer in women in Barcelona, Spain, Eur. J. Cancer, 33(8):1256-1261, 1997.

2. Cohen JH, Kristal AR, Stanford JL: Fruit and vegetable intake and prostate cancer risk, J. Natl. Cancer Inst., 92(1):61-68, 2000.

3. Day GL, Shore RE, Blot WJ, McLaughlin JK, Austin DF, Greenberg RS, Liff JM, Preston-Martin S, Sarkar S, Schoenberg JB et al: Dietary factors and second primary cancers: a follow-up of oral and pharyngeal cancer patients, Nutr. Cancer, 21(3):223-232, 1994.

4. Joshipura KJ, Ascherio A, Manson JE, Stampfer MJ, Rimm EB, Speizer FE, Hennekens CH, Spiegelman D, Willett WC: Fruit and vegetable intake in relation to risk of ischemic stroke, JAMA, 282(12):1233-1239, 1999.

5. Michaud DS, Spiegelman D, Clinton SK, Rimm EB, Willett WC, Giovannucci EL: Fruit and vegetable intake and incidence of bladder cancer in a male prospective cohort, J. Natl. Cancer Inst., 91(7):605-613, 1999.

6. Pratt S: Dietary prevention of age-related macular degeneration, J. Am. Optom. Assoc., 70(1):39-47, 1999.

7. Seddon JM, Ajani UA, Sperduto RD, Hiller R, Blair N, Burton TC, Farber MD, Gragoudas ES, Haller J, Miller DT, et al: Dietary carotenoids, vitamins A, C, and E, and advanced age-related macular degeneration. Eye Disease Case-Control Study Group, JAMA, 272(18):1413-1420, 1994.

8. Verhagen H, Poulsen HE, Loft S, Van Poppel G, Willems MI, Van Bladeren PJ: Reduction of oxidative DNA-damage in humans by brussels sprouts, Carcinogenesis, 16(4):969-970, 1995.

9. Witte JS, Longnecker MP, Bird CL, Lee ER, Frankl HD, Haile RW: Relation of vegetable, fruit, and grain consumption to colorectal adenomatous polyps, Am. J. Epidemiol., 144(11):1015-1025, 1996.

10. Yuan JM, Gago-Dominguez M, Castelao JE, Hankin JH, Ross RK, Yu MC: Cruciferous vegetables in relation to renal cell carcinoma, Int. J. Cancer, 77(2):211-216, 1998.

Dairy products:

11. Baker A, Harvey L, Majask-Newman G, Fairweather-Tait S, Flynn A, Cashman : Effect of dietary copper intakes on biochemical markers of bone metabolism in healthy adult males, Eur. J. Clin. Nutr., 53(5):408-412, 1999.

12. Branca F: Physical activity, diet and skeletal health, Public Health Nutr., 2(3A):391-396, 1999.

13. Lewis RD, Modlesky CM: Nutrition, physical activity, and bone health in women, Int. J. Sports Nutr., 8(3):250-284, 1998.

14. New SA, Robins SP, Campbell MK, Martin JC, Garton MJ, Bolton-Smith C, Grubb DA, Lee SJ, Reid DM: Dietary influences on bone mass and bone metabolism: further evidence of a positive link between fruit and vegetable consumption and bone health?, Am. J. Clin. Nutr., 71(1):142-151, 2000.

15. Wang MC, Moore EC, Crawford PB, Hudes M, Sabry ZI, Marcus R, Bachrach LK: Influence of pre-adolescent diet on quantitative ultrasound measurements of the calcaneus in young adult women, Osteoporos. Int., 9(6):532-535, 1999.

NUTRITION Q&A

Protein for Weight Reduction

1. St. Jeor ST, Howard BV, Prewitt TE, Bovee V, Bazzarre T, Eckel RH: Dietary protein and weight reduction: A statement for healthcare professionals from the Nutrition Committee of the Council on Nutrition, Physical Activity, and Metabolism of the American Heart Association, Circulation, 104(15):1869-1874, 2001.

Homocysteine

1. Castelli WP: Lipids, risk factors and ischaemic heart disease, Atherosclerosis, 124S:1-9, 1996.

2. Fallon UB, Ben-Shlomo Y, Elwood P, Ubbink JB, Smith GD: Homocysteine and coronary heart disease in the Caerphilly cohort: a 10 year follow up, Heart, 85(2):153-158, 2001.

3. Malinow MR, Bostom AG, Krauss RM: Homocyst(e)ine, diet, and cardiovascular diseases: A statement for healthcare professionals from the Nutrition Committee, American Heart Association, Circulation, 99:178-182, 1999.

4. Maxwell SR: Coronary artery disease -- free radical damage, antioxidant protection and the role of homocysteine, Basic Res. Cardiol., 95S:165-171, 2000.

5. Seman LJ, McNamara JR, Schaefer EJ: Lipoprotein(a), homocysteine, and remnantlike particles: emerging risk factors, Curr. Opin. Cardiol., 14(2):186-191, 1999.

6. Taylor BV, Oudit GY, Evans M: Homocysteine, vitamins, and coronary artery disease. Comprehensive review of the literature, Can. Fam. Physician, 46:2236-2245, 2000.

7. Witte KK, Clark AL, Cleland JG: Chronic heart failure and micronutrients, J. Am. Coll. Cardiol., 37(7):1765-1774, 2001.

Vitamin C/Vitamin E/Iron Absorption

1. Combs JF Jr, Pesti GM: Influence of ascorbic acid on selenium nutrition in the chick, J. Nutr., 106(7):958-966, 1976.

2. Pace V, Iannucci E: The importance of vitamins in relation to the presence of heavy metals in food, Panminerva Med., 36(2):80-82, 1994.

3. Srigiridhar K, Nair KM: Supplementation with alpha-tocopherol or a combination of alpha-tocopherol and ascorbic acid protects the gastrointestinal tract of iron-deficient rats against iron-induced oxidative damage during iron repletion, Br. J. Nutr., 84(2):165-173, 2000.

Weight Loss & Breakfast

1. Gluck ME, Geliebter A, Satov T:: Night eating syndrome is associated with depression, low self-esteem, reduced daytime hunger, and less weight loss in obese outpatients, Obes. Res., 9(4):264-267, 2001.

2. Keim NL, Canty DJ, Barbieri TF, Wu MM: Effect of exercise and dietary restraint on energy intake of reduced-obese women, Appetite, 26(1):55-70, 1996.

3. O'Dea JA, Caputi P: Association between socioeconomic status, weight, age and gender, and the body image and weight control practices of 6- to 19-year-old children and adolescents, Health Educ. Res., 16(5):521-532, 2001.

4. Schlundt DG, Hill JO, Sbrocco T, Pope-Cordle J, Sharp T: The role of breakfast in the treatment of obesity: a randomized clinical trial, Am. J. Clin. Nutr., 55(3):645-651, 1992.

Ghrelin & Gastric Bypass

1. Cummings DE, Weigle DS, Frayo RS, Breen PA, Ma MK, Dellinger EP, Purnell JQ: Plasma ghrelin levels after diet-induced weight loss or gastric bypass surgery, New Engl. J. Med., 346(21):1623-1630, 2002.

2. Kojima M, Hosoda H, Date Y, Nakazato M, Matsuo H, Kangawa K: Ghrelin is a growth-hormone-releasing acrylated peptide from stomach, Nature, 402(6762):656-660, 1999.

3. Nguyen NT, Goldman C, Rosenquist CJ, Arango A, Cole CJ, Lee SJ, Wolfe BM: Laparoscopic versus open bypass: a randomized study of outcomes, quality of life, and costs, Ann. Surg., 234(4):279-291, 2001.

4. Nguyen NT, Lee SL, Goldman C, Fleming N, Arango A, McFall R, Wolfe BM: Comparison of pulmonary function and postoperative pain after laparoscopic versus open gastric bypass: a randomized trial, J. Am. Coll. Surg., 192(4):469-476, 2001.

5. Sugerman HJ: Bariatric surgery for severe obesity, J. Assoc. Acad. Minor Phys., 12(3):129-136, 2001.

6. Westling A, Bergqvist D, Bostrom A, Karacagil S, Gustavsson S: Incidence of deep venous thrombosis in patients undergoing obesity surgery, World J. Surg., 26(4):470-473, 2002.

Dopamine & Food Addiction

1. Volkow ND, Wang GJ, Fowler JS, Logan J, Jayne M, Franceschi D, Wong C, Gatley SJ, Gifford AN, Ding YS, Pappas N: "Nonhedonic" food motivation in humans involves dopamine in the dorsal striatum and methylphenidate amplifies this effect, Synapse, 44(3):175-180, 2002.

ACTIVITY

1. Harris JE: The role of physical activity in the management of obesity, J. Am. Osteopath. Assoc., 99(4):S15-S19, 1999.

2. Klem ML: Successful losers. The habits of individuals who have maintained long-term weight loss, Minn. Med., 83(11):43-45, 2000.

3. Klem ML, Wing RR, McGuire MT, Seagle HM, Hill JO: A descriptive study of individuals successful at long-term maintenance of substantial weight loss, Am. J. Clin. Nutr., 66(2):239-246, 1997.

4. McGuire MT, Wing RR, Klem ML, Seagle HM, Hill JO: Long-term maintenance of weight loss: do people who lose weight through various weight loss methods use different behaviors to maintain their weight?, Int. J. Obes. Relat. Metab. Disord., 22(6):572-577, 1998.

5. McInnis KJ: Exercise and obesity, Coron. Artery Dis., 11(2):111-116, 2000.

6. Rippe JM, Hess S: The role of physical activity in the prevention and management of obesity, J. Am. Diet. Assoc., 98(10Suppl2):S31-S38, 1998.

7. Saris WH: Fit, fat and fat free: the metabolic aspects of weight control, Int. J. Obes. Relat. Metab. Disord., 22:S15-S21, 1998.

8. Sarlio-Lahteenkorva S, Rissanen A: Weight loss maintenance: determinants of long-term success, Eat Weight Disord., 3(3):131-135, 1998.

9. Shephard RJ: Absolute versus relative intensity of physical activity in a dose-response context, Med. Sci. Sports Exerc., 33(6):S400-S418, 2001.

10. Tremblay A, Doucet E, Imbeault P: Physical activity and weight maintenance, Int. J. Obes. Relat. Metab. Disord., 23:S50-S54, 1999.

11. Weyer C, Linkeschowa R, Heise T, Giesen HT, Spraul M: Implications of the traditional and the new ACSM physical activity recommendations on weight reduction in dietary treated obese patients, Int. J. Obes. Relat. Metab. Disord., 22(11):1071-1078, 1998.

ACTIVITY Q&A

MSM for arthritis

1. Bradley H, Gough A, Sokhi RS, Hassell A, Waring R, Emery P: Sulfate metabolism is abnormal in patients with rheumatoid arthritis. Confirmation by in vivo biochemical findings, J. Rheumatol., 21(7):1192-1196, 1994.

2. Ekmekcioglu C, Strauss-Blasche G, Holzer F, Marktl W: Effect of sulfur baths on antioxidant defense systems, peroxide concentrations and lipid levels in patients with degenerative osteoarthritis, Forsch. Komplementarmed. Klass Naturheilkd., 9(4):216-220, 2002.

3. Emery P, Bradley H, Arthur V, Tunn E, Waring R:: Genetic factors influencing the outcome of early arthritis - the role of sulphoxidation status, Br. J. Rheumatol., 31(7):449-451, 1992.

4. Emery P, Bradley H, Gough A, Arthur V, Jubb R, Waring R: Increased prevalence of poor sulphoxidation in patients with rheumatoid arthritis: effect of changes in the acute phase response and second line drug treatment, Ann. Rheum. Dis., 51(3):318-320, 1992.

5. Habata T, Ohgushi H, Takakura Y, Tohno Y, Moriwake Y, Minami T, Fujisawa Y: Relationship between meniscal degeneration and element contents, Biol. Trace Elem. Res., 79(3):247-256, 2001.

6. Sharif M, Osborne DJ, Meadows K, Woodhouse SM, Colvin EM, Shepstone L, Dieppe PA: The relevance of chondroitin and keratan sulphate markers in normal and arthritic synovial fluid, Brit. J. Rheumatol., 35(10):951-957, 1996.

7. Yamada H, Miyauchi S, Morita M, Yoshida Y, Yoshihara Y, Kikuchi T, Washimi O, Washimi Y, Terada N, Seki T, Fujikawa K: Content and sulfation pattern of keratan sulfate in hip osteoarthritis using high performance liquid chromatography, J. Rheumatol., 27(7):1721-1724, 2000.

8. www.schiffvitamins.com/productsearch_results.asp?p=80.

Glucosamine/Chondroitin for arthritis

1. Ma L, Rudert WA, Harnaha J, Wright M, Machen J, Lakomy R, Qian S, Lu L, Robbins PD, Trucco M, Giannoukakis N: Immunosuppressive effects of glucosamine, J. Biol. Chem., 277(42):39343-39349, 2002.

2. Murad H, Tabibian MP: The effect of an oral supplement containing glucosamine, amino acids, minerals, and antioxidants on cutaneous aging: a preliminary study, J. Dermatolog. Treat., 12(1):47-51, 2001.

3. Nakayama Y, Narita T, Mori A, Uesaka S, Miyazaki K, Ito H: The effects of age and sex on chondroitin sulfates in normal synovial fluid, Arthritis Rheum., 46(8):2105-2108, 2002.

4. Pavelka K, Gatterova J, Olejarova M, Machacek S, Giacovelli G, Rovati LC: Glucosamine sulfate use and delay of progression of knee osteoarthritis: a 3-year, randomized, placebo-controlled, double-blind study, Arch. Intern. Med., 162(18):2113-2123, 2002.

5. Verbruggen G, Goemaere S, Veys EM: Systems to assess the progression of finger joint osteoarthritis and the effects of disease modifying osteoarthritis drug, Clin. Rheumatol., 21(3):231-243, 2002.

6. Volpi N: Oral bioavailability of chondroitin sulfate (Condrosulf) and its constituents in healthy male volunteers, Osteoarthritis Cartilage, 10(10):768-777, 2002.

7. Wu-Wong JR, Berg CE, Dayton BD: Endothelin-stimulated glucose uptake: effects of intracellular Ca(2+), cAMP andn glucosamine, Clin. Sci., 103(S48):418S-423S, 2002.

8. www.consumerreports.org/main/detail.jsp?CONTENT%3C%3Ecnt_id=137617&FOLDER%3C%3Efolder_id=21135&bmUID=1008604478357.

THE CALCULATORIE

1. Heyward VH: Advanced Fitness Assessment & Exercise Prescription, 3rd ed., Appendix E, 1998.

STRESS REDUCTION

1. Moore PJ, Adler NE, Williams DR, Jackson JS: Socioeconomic status and health: the role of sleep, Psychosom. Med., 64(2):337-344, 2002.

STRESS Q&A

Stress & Disease

1. Birketvedt GS, Florholmen J, Sundsfjord J, Osterud B, Dinges D, Bilker W, Stunkard A: Behavioral and neuroendocrine characteristics of the night-eating syndrome, JAMA, 282(7):657-663, 1999.

2. Brindley DN: Role of glucocorticoids and fatty acids in the impairment of lipid metabolism observed in the metabolic syndrome, Int. J. Obes. Relat. Metab. Disord., 19S(1):S69-S75, 1995.

3. Cacioppo JT, Berntson GG, Malarkey WB, Kiecolt-Glaser JK, Sheridan JF, Poehlmann KM, Burleson MH, Ernst JM, Hawkley LC, Glaser R: Autonomic, neuroendocrine, and immune responses to psychological stress: the reactivity hypothesis, Ann. N.Y. Acad. Sci., 840:664-673, 1998.

4. Jezova D, Jurankova E, Mosnarova A, Kriska M, Skultetyova I: Neuroendocrine response during stress with relation to gender differences, Acta Neurobiol. Exp., 56(3):779-785, 1996.

5. Khani S, Tayek JA: Cortisol increases gluconeogenesis in humans: its role in the metabolic syndrome, Clin. Sci., 101(6):739-747, 2001.

6. Lee ZS, Critchley JA, Tomlinson B, Young RP, Thomas GN, Cockram CS, Chan TY, Chan JC: Urinary epinephrine and norephinephrine interrelations with obesity, insulin, and the metabolic syndrome in Hong Kong Chinese, Metabolism, 50(2):135-143, 2001.

7. McEwen BS: Allostasis, allostatic load, and the aging nervous system: role of excitatory amino acids and excitotoxicity, Neurochem. Res., 25(9-10):1219-1231, 2000.

8. McEwen BS: Stress, adaptation, and disease. Allostasis and allostatic load, Ann. N.Y. Acad. Sci., 840:33-44, 1998.

9. McEwen BS, Stellar E: Stress and the individual. Mechanisms leading to disease, Arch. Intern. Med., 153(18):2093-2101, 1993.

10. Seeman TE, Singer BH, Rowe JW, Horwitz RI, McEwen BS: Price of adaptation -- allostatic load and its health consequences. MacArthur studies of successful aging, Arch. Intern. Med., 157(19):2259-2268, 1997.

11. Sheridan JF, Dobbs C, Brown D, Zwilling B: Psychoneuroimmunology: stress effects on pathogenesis and immunity during infection, Clin. Microbiol. Res., 7(2):200-212, 1994.

12. Tilders FJ, Schmidt ED, Hoggendijk WJ, Swaab DF: Delayed effects of stress and immune activation, Baillieres Best Pract. Res. Clin. Endocrinol. Metab., 13(4):532-540, 1999.

ENVIRONMENT Q&A

Antiperspirants & Breast Cancer

1. Robb-Nicholson C: By the way, doctor, I recently received an e-mail warning...., Harv. Women's Health Watch, 8(7):7, 2001.

Talc & Cancer

1. De Campos JR, Vargas FS, De Campos Werebe E, Cardoso P, Teixeira LR, Jatene FB, Light RW: Thoracoscopy talc poudrage: a 15-year experience, Chest, 119(3):801-806, 2001.

2. Faerstein F, Szklo M, Rosenshein NB: Risk factors for uterine leiomyoma: a practice-based case-control study. II. Atherogenic risk factors and potential sources of uterine irritation, Am. J. Epidemiol., 153(1):11-19, 2001.

3. Gamble JF: A nested case control study of lung cancer among New York talc workers, Int. Arch. Occup. Environ. Health, 64(6):449-456, 1993.

4. Gertig DM, Hunter DJ, Cramer DW, Colditz GA, Speizer FE, Willet WC, Hankinson SE: Prospective study of talc use and ovarian cancer, J. Natl. Cancer Inst., 92(3):249-252, 2000.

5. Holthouse DJ, Chleboun JO: Talc serodesis -- report of four cases, J.R. Coll. Surg. Edinb., 46(4):244-245, 2001.

6. La Vecchia C: Epidemiology of ovarian cancer: a summary review, Eur. J. Cancer Prev., 10(2):125-129, 2001.

7. Leyden JJ: Corn starch, Candida albicans, and diaper rash, Pediatr. Dermatol., 1(4):322-325, 1984.

8. Meisler JG: Toward optimal health: the experts discuss ovarian cancer, J. Womens Health Gend. Based Med., 9(7):705-710, 2000.

9. Nasreen , Mohammed KA, Dowling PA, Ward MJ, Galffy G, Antony VB: Talc induces apoptosis in human malignant mesothelioma cells in vitro, Am. J. Respir. Crit. Care Med., 161(2 Pt 1):595-600, 2000.

10. Ness RB, Grisso JA, Cottreau C, Klapper J, Vergona R, Wheeler JE, Morgan M, Schlesselman JJ: Factors related to inflammation of the ovarian epithelium and risk of ovarian cancer, Epidemiology, 11(2):111-117, 2000.

11. Rosenblatt KA, Mathews WA, Daling JR, Voigt LF, Malone K: Characteristics of women who use perineal powders, Obstet. Gynecol., 92(5):753-756, 1998.

12. Runeman B, Faergemann J, Larko O: Experimental Candida albicans lesions in healthy humans: dependence on skin pH, Acta Derma. Venereol., 80(6):421-424, 2000.

13. Straif K, Keil U, Taeger D, Holthenrich D, Sun Y, Bungers M, Weiland SK: Exposure to nitrosamines, carbon black, asbestos and talc and mortality from stomach, lung, and laryngeal cancer in a cohort of rubber workers, Am. J. Epidemiol., 152(4):297-306, 2000.

14. Tzonou A, Polychronopoulou A, Hsieh CC, Rebelakos A, Karakatsani A, Trichopoulos D: Hair dyes, analgesics, tranquilizers and perineal talc application as risk factors for ovarian cancer, Int. J. Cancer, 55(3):408-410, 1993.

15. Wehner AP: Biological effects of cosmetic talc, Food Chem. Toxicol., 32(12):1173-1184, 1994.

16. Whysner J, Mohan M: Perineal application of talc and cornstarch powders: evaluation of ovarian cancer risk, Am. J. Obstet. Gynecol., 182(3):720-724, 2000.

This page was last updated on 04/23/03.

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